Repeat procedures after pulsed field ablation for atrial fibrillation: MANIFEST-REDO study.

Europace · 2025 · PMC12344414 · PMID 39824172

Europe PMC DOI

hedged sentences

0.0700

closest p · 1.4× alpha

0.0700

boldest claim

The sentences

borderline significanceP = 0.07so close (0.05 < p ≤ 0.1)

In the subgroup of patients with persistent AF, there was borderline significance in secondary effectiveness with the use of posterior wall ablation (68% vs. 51%, P = 0.07).

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near-significantno p-value reported

While our study showed a near-significant effectiveness of posterior wall ablation in PersAF patients, this finding is at best hypothesis generating: this near-significant finding was achieved in patients undergoing repeat (not initial) ablation, with difference in subgroups in terms of baseline characteristics, lesion set during initial ablation, and ablation energy used during repeat ablation.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.