IFNγ-inducible Gbp4 and Irgb6 contribute to experimental cerebral malaria pathology in the olfactory bulb.

The relative expression of Gbp4 was significantly reduced (** P < 0.01), while Irgb6 and Gbp5 showed a trend toward reduction ( P = 0.067), but no change was observed in Ly6a or Zbp1 expression in infected IFN-γR −/− mice compared to wild-type (WT) controls ( Fig. 2A ).

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