Risk Factors for Radiation-Induced Keratoconjunctivitis Sicca in Dogs Treated with Hypofractionated Intensity-Modulated Radiation Therapy for Intranasal Tumors.

As shown in Figure 4 , ROC analysis of D 50 for the eyeball (AUC = 0.83, 95% confidence interval [CI]; 0.67–1.00, p = 0.015), cornea (AUC = 0.82, 95% CI; 0.64–0.99, p = 0.020), and retina (AUC = 0.87, 95% CI; 0.72–1.00, p = 0.007) showed significant predictive power for the development of KCS, whereas that for the eyelid did not reach statistical significance (AUC = 0.73, 95% CI; 0.51–0.96, p = 0.088).

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