Cardioprotective Role of Captopril: From Basic to Applied Investigations.

Int J Mol Sci · 2025 · PMC12346263 · PMID 40806350

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did not reach statistical significanceno p-value reported

In a randomized placebo-controlled trial of oral captopril and mononitrate treatment, early initiation of captopril in MI resulted in a reduction in ventricular extrasystoles and the frequency of multiple extrasystoles over 48 h of Holter ECG monitoring, though these effects did not reach statistical significance when compared to the placebo group [ 252 ].

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