Exploring the Association Between Platelet Count, the Systemic Immune Inflammation Index, and Fracture Risk in Postmenopausal Women with Osteoporosis: A Cross-Sectional Study.

Univariate regression analysis revealed the following significant associations: chronological age was positively associated with PDW (r = 0.188, p = 0.047) and P-LCR (r = 0.208, p = 0.03); the 10 yr hip fracture risk was positively associated with NLR (r = 0.3, p = 0.02) and SII (r = 0.35, p = 0.007); the lumbar spine BMD was negatively associated with platelet count (r = −0.284, p = 0.003) and showed a trend with PCT (r = −0.206, p = 0.074); vitamin D status was negatively associated with P-LCC (r = −0.301, p = 0.034); NLR was positively associated with PLT count (r = 0,02; p = 0.35). 4.

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However, a borderline significant difference was noted in the 10 yr probability of hip fracture, which was higher in the group with the elevated platelet count (7.4% vs. 4.5%, p = 0.08).

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