Early Positive Fluid Balance Associates with Increased Mortality in Neurological Critically Ill Patients: A 10-Year Cohort Study.

From the association plot between fluid balance on day 1 and the predicted probability of 28-day mortality, the predicted probability of mortality showed a relatively stable pattern in the negative fluid balance range but demonstrated an increasing trend with more positive fluid balance ( Figure 3 ).

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Further analysis of mean fluid balance over extended periods (up to days 3, 5, and 7) suggested a trend towards increased 28-day mortality with higher fluid balance, although these associations did not reach statistical significance.

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