Kidney Transplant Outcomes in Recurrent Versus <i>De Novo</i> IgA Nephropathy.

In a multivariable analysis of T1–2, C1–2, and > 1+ glomerular C3 staining, the former 2 variables were independent predictors of graft loss with hazard ratios of 3.18 and 3.70 and P -values of 0.0103 and 0.0012, respectively, whereas C3 staining did not quite reach statistical significance ( P = 0.0585) despite a robust hazard ratio of 2.32.

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Graft survival was worse in patients with recurrent IgAN than in those with de novo IgAN ( Figure 1 ), although this did not reach statistical significance ( P = 0.106 by log-rank test and 0.072 by Wilcoxon, the latter giving somewhat greater emphasis to the earlier follow-up period).

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