Oat Fiber Alleviates Loperamide-Induced Constipation in Mice by Modulating Intestinal Barrier Function.

Compared with the MODEL group, following oral administration of oat fiber, SS levels in the LOW and MIDDLE groups were significantly reduced ( p < 0.05), while the HIGH group of constipated mice exhibited a highly significant decrease in somatostatin concentration ( p < 0.001) ( Figure 3 E). 3.5.

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When compared to the MODEL group, the low-dose group (LOW) showed an increase in small intestinal transit activity; however, this change did not reach statistical significance ( p > 0.05).

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