Inflammatory markers CRP and WBC as predictors of liver function impairment in multiple injury trauma patients: a repeated measures analysis.

In Model 2, after further adjustment for drinking history, gender, age and BMI, CRP ≥ 40 mg/L remained the only independent predictor of AST elevation ( B = 0.788; OR = 2.20; 95% CI, 1.15–4.20; p = 0.017), while CRP 10–40 mg/L again failed to achieve significance ( B = 0.302; p = 0.200).

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By contrast, the 24 h time point (OR = 1.113; p = 0.641), White Blood Cell Count > 10 × 10 9 /L (OR = 0.851; p = 0.484), ISS strata (16–25: OR = 1.187; p = 0.706; ≥ 25: OR = 1.174; p = 0.697), CRP 10–40 mg/L (OR = 1.007; p = 0.980), neutrophil–lymphocyte ratio (OR = 0.988; p = 0.496), lymphocyte–monocyte ratio (OR = 1.005; p = 0.783), BMI > 24 kg/m^2 (OR = 0.587; p = 0.193), drinking history and gender all failed to reach significance.

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Time point (24 h or 72 h), ISS category and CRP group did not reach statistical significance.

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