AURKB and PI3K/AKT/mTOR pathways converge to regulate <i>TERT</i> expression.

iScience · 2025 · PMC12356326 · PMID 40822359

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a positive trendno p-value reported

A positive trend was observed among lines bearing BRAF V600E or RET mutations, but the HRAS p.G13R–mutated C643 cells—despite exhibiting the highest TERT levels—showed minimal MAPK pathway activity.

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did not reach statistical significanceno p-value reported

However, this correlation did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

AURKB and PI3K/AKT/mTOR pathways converge to regulate &lt;i&gt;TERT&lt;/i&gt; expression.

The sentences

AURKB and PI3K/AKT/mTOR pathways converge to regulate <i>TERT</i> expression.