Based on this metabolite information, an unsupervised principal component analysis model showed a clear trend of separation between the ADAMTS9-AS2-Exos treatment group and the control group in both the cationic and anionic modes, indicating that the two groups were different in terms of metabolite composition ( Fig. 6 B, C).
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lncRNA ADAMTS9-AS2/let-7a-5p axis regulates metabolic reprogramming by targeting HK2 in oral submucous fibrosis-associated oral squamous cell carcinoma.
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