Proteogenomic characterization of invasive breast tumors in young women.

NPJ Breast Cancer · 2025 · PMC12361583 · PMID 40826002

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hedged sentences

0.3840

closest p · 7.7× alpha

0.3840

boldest claim

The sentences

did not reach statistical significancep = 0.384not close (p > 0.1)

While TP53-mutated luminal cancers did show a numerically worse outcome compared to their non-mutated counterparts, the difference did not reach statistical significance ( p = 0.384; HR = 2.19, using non-mutated as the reference group; Fig.

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a trend toward significanceno p-value reported

We found that LIG1 was more frequently deleted in tumors from young women, showing a trend toward significance but not reaching statistical significance in the overall comparison ( p = 0.057) and in the Basal subtype ( p = 0.056) (Fig.

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