Barely Significant
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Is highly purified cannabidiol a treatment opportunity for drug-resistant epilepsy in subjects with typical Rett syndrome and CDKL5 deficiency disorder?

Epilepsia Open · 2025 · PMC12362169 · PMID 40543048

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a strong trendno p-value reported
DISCUSSION Our findings suggest a strong trend toward the efficacy of CBD in reducing seizure frequency, with 66.6% of subjects experiencing a ≥50% reduction and 25.9% achieving a >75% reduction.

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