Immune intrinsic escape signature stratifies prognosis, characterizes the tumor immune microenvironment, and identifies tumorigenic PPP1R8 in glioblastoma multiforme patients.

However, in multivariate analyses of these validation sets, IEScore did not reach statistical significance for OS prediction, likely due to the limited number of surviving patients, given the aggressive nature of GBM ( Figures 3D, F ).

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