The impact of blood MCP-1 levels on Alzheimer's disease with genetic variation at the NAV3 and UNC5C loci.

Transl Psychiatry · 2025 · PMC12365253 · PMID 40830334

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hedged sentence

0.3900

closest p · 7.8× alpha

0.3900

boldest claim

The sentences

did not reach statistical significancep = 0.39not close (p > 0.1)

Similarly, the MCP-1 concentration was positively associated with AD incidence among UNC5C rs72659964-AT + TT carriers (OR = 32.84, 95% CI = 4.15, 380.14; p = 0.002), but this trend was largely attenuated and did not reach statistical significance for the UNC5C rs72659964-AA carriers (p = 0.39).

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