IRE1α modulates M1 oncolytic virus sensitivity via ER stress regulation in bladder cancer.

Cancer Drug Resist · 2025 · PMC12366421 · PMID 40843354

Europe PMC DOI

hedged sentence

0.0650

closest p · 1.3× alpha

0.0650

boldest claim

The sentences

did not reach statistical significanceP = 0.065so close (0.05 < p ≤ 0.1)

Although TCGA analysis suggested a trend toward poorer prognosis in patients with low IRE1α expression, the association did not reach statistical significance ( P = 0.065), warranting validation in larger and independent cohorts.

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