The landscape of germline variants in breast and colorectal cancer susceptibility genes in patients with pituitary tumours.

J Neurooncol · 2025 · PMC12367850 · PMID 40563065

Europe PMC DOI

hedged sentence

0.0570

closest p · 1.1× alpha

0.0570

boldest claim

The sentences

did not reach statistical significancep = 0.057so close (0.05 < p ≤ 0.1)

The difference in the rate of pathogenic variants in cancer susceptibility genes between individuals with and without P/LP variants in a classical pituitary tumour predisposition gene approached but did not reach statistical significance ( p = 0.057).

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