Effect of Age and Gender on Corneal Epithelial Thickness in Refractive Surgery Candidates.

The study found that the CET of the central cornea (2 mm), paracentral, and mid-peripheral zones (2–5 and 5–6 mm, respectively) showed highly significant thinning with age (P <0.001) for both males and females, with no significant difference between the genders.

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Significant age-related differences in epithelial thickness were observed, with older age associated with thicker epithelium in all quadrants except the central zone, where the thickness was greater but did not reach statistical significance ( Figure 2A ).

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