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High-affinity transferrin receptor binding improves brain delivery of bispecific antibodies at tracer dose.

Fluids Barriers CNS · 2025 · PMC12369151 · PMID 40842024

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showed a trendno p-value reported
The blood kinetics were comparable between WT and App NL−G−F mice for each antibody and showed a trend that stronger affinity to mTfR resulted in quicker blood elimination (Fig. 2 B; Table 3 ).

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