Hybrid molecule SA-10 and its PLGA nanosuspension protect human and rodent retinal ganglion cells against neuronal injury.

BMC Neurosci · 2025 · PMC12369271 · PMID 40836213

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did not reach statistical significanceno p-value reported

Although our results indicate a trend toward reduced mRNA expression of pro-inflammatory markers NFKB1 and TNF-α following SA-10-NP treatment, these changes did not reach statistical significance.

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an increasing trendno p-value reported

SA-10-NP treatment showed an increasing trend in the preservation of GCL cells (22.7%) and GCC thickness (22.31%) in female mice compared to the blank NP treatment (Fig. 7 B).

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