Functional deletion of α7 nicotinic acetylcholine receptor impairs Ca<sup>2+</sup>-dependent glutamatergic synaptic transmission by affecting both presynaptic and postsynaptic protein expression and function.

Front Physiol · 2025 · PMC12370769 · PMID 40861894

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0.1640

closest p · 3.3× alpha

0.1640

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did not reach statistical significancep = 0.164not close (p > 0.1)

However, the AMPA/NMDA ratio differences between WT neurons (0.92 ± 0.22) and α7-KO ones (1.14 ± 0.24) did not reach statistical significance (p = 0.164; Figures 2F,I ).

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Functional deletion of α7 nicotinic acetylcholine receptor impairs Ca&lt;sup&gt;2+&lt;/sup&gt;-dependent glutamatergic synaptic transmission by affecting both presynaptic and postsynaptic protein expression and function.

The sentences

Functional deletion of α7 nicotinic acetylcholine receptor impairs Ca<sup>2+</sup>-dependent glutamatergic synaptic transmission by affecting both presynaptic and postsynaptic protein expression and function.