In our cohort, the level of glycoprotein acetyls, marker of low-grade inflammation associated with antenatal depression and GDM in overweight and obese women (Lahti-Pulkkinen et al., 2020 ), showed an increasing trend at delivery in SSRI users.
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Longitudinal metabolic profiling of women using selective serotonin reuptake inhibitors during pregnancy.
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In our study, we observed a decreasing trend in glucose levels and the amino acid glycine in SSRI users during the first trimester and at delivery, respectively.
They also showed a trend of decreased glycine, degree of unsaturation of fatty acids, the ratio of omega-6 fatty acids and linoleic acids to total fatty acids, and the ratio of polyunsaturated fatty acids to monounsaturated fatty acids (Figure S2).