Risk Stratification in Acute Coronary Syndromes: The Systemic Immune-Inflammation Index as Prognostic Marker.

Med Sci (Basel) · 2025 · PMC12371994 · PMID 40843738

Europe PMC DOI

hedged sentence

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closest p · 1.4× alpha

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boldest claim

The sentences

did not reach statistical significancep = 0.07so close (0.05 < p ≤ 0.1)

For a combined parameter GRACE 2 score and SII, ROC curve analysis revealed an AUC of 0.907 (95% CI 0.846–0.950), with an increased specificity 91.04%, sensitivity 77.14%, but the improvement of AUC for the combined parameter compared to AUC for GRACE 2 score did not reach statistical significance ( p = 0.07) ( Figure 4 b).

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