Hippocampal Volumetric Changes in Astronauts Following a Mission in the International Space Station.

Although only the left anterior subregion and the right body subregion reached statistical significance in volume loss, it is relevant to note that both the left body and right anterior subregions showed a trend toward significance ( p = 0.108 and p = 0.184, respectively), whereas the posterior subregions in both the left and right hippocampus were far from it ( p = 0.667 and p = 0.875, respectively).

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It is important to address an apparent discrepancy in our findings: while we observed a significant sex-based difference in volume change in the whole right hippocampus, this difference did not reach statistical significance at the subregion level.

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