Identification and Validation of Genes Involved in Energy Metabolism in Polycystic Ovary Syndrome.

Although GPC4 and HS2ST1 did not reach statistical significance (P = 0.1306 and P = 0.2945, respectively), moderate effect size differences and their known roles in insulin signaling and heparan sulfate modification suggest functional relevance that warrants further investigation in larger cohorts.

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