The JAK2 V617F VAF was generally maintained across both HD and ET MSC‐pre‐seeded scaffolds, with a slight trend towards a higher JAK2 V617F mutation burden in the ET MSC‐pre‐seeded scaffolds, though this result did not reach statistical significance (Figure 3E ).
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Mesenchymal stromal cells from <i>JAK2</i> <sup><i>V617F</i></sup> myeloproliferative neoplasms support healthy and malignant hematopoiesis in a humanized scaffold model in vivo.
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