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Flecainide mediated sodium channel blockade enhances blood brain barrier integrity and promotes neuroprotection in neuroinflammation.

Sci Rep · 2025 · PMC12375043 · PMID 40849530

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However, there was a noticeable trend suggesting that flecainide may have beneficial effects on myelination and neuronal survival, as indicated by increased MBP and Brn3a expression, though these changes did not reach statistical significance.

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