TCR and BCR repertoire analysis reveals distinct signatures between benign and malignant ovarian tumors.

Further analysis identified 75 V-J pairs with differential abundance (p<0.05, uncorrected), including 16 highly significant pairs (p<0.01), though these exploratory findings remain uncorrected for multiple testing due to sample size limitations and require validation in larger cohorts ( Figure 5A ).

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However, these correlations did not reach statistical significance (p > 0.05 for all) in our cohort of 20 participants.

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