Diagnostic accuracy of circulating tumor DNA for detection of ALK rearrangement in lung cancer: A systematic review and meta-analysis of 14 studies.

PLoS One · 2025 · PMC12377591 · PMID 40853979

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showed a trendno p-value reported

However, the specimen volume showed a trend toward higher sensitivity with volumes ≥3 mL (1.00) compared to <3 mL (0.67), though the number of studies in the ≥ 3 mL group was limited (n = 2).

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