NRF2 agonists 4-octyl-itaconate and dimethyl fumarate reduce human and bovine RSV proliferation and RSV disease in a murine model.

Immunohorizons · 2025 · PMC12377912 · PMID 40854594

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hedged sentence

0.0509

closest p · 1.0× alpha

0.0509

boldest claim

The sentences

showed a trendP = 0.0509so close (0.05 < p ≤ 0.1)

DMF-treated animals showed a trend toward reduced airway infiltration ( P = 0.0509) but no reduction in consolidated lung pathology, indicating that the treatment did not reduce lung damage after hRSV infection.

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