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Hospital-Wide Implementation, Clinical Outcomes, and Safety of Phenobarbital for Alcohol Withdrawal.

JAMA Netw Open · 2025 · PMC12379078 · PMID 40853658

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After implementation, AWS symptom control (after day 0), treatment duration, and time to discharge all improved significantly, with no evidence of adverse safety effects; rather, trends suggested potential reductions in prolonged use of physical restraints and intubation, although estimates did not reach statistical significance.

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