Disease-specific U1 spliceosomal RNA mutations in mature B-cell neoplasms.

Leukemia · 2025 · PMC12380619 · PMID 40588565

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showed a trendp = 0.069so close (0.05 < p ≤ 0.1)

Among patients analyzed prior to any therapy, the g.3A>C U1 mutation showed a trend for enrichment in patients diagnosed with CLL compared to monoclonal B-cell lymphocytosis (MBL) (26/850 (3.1%) vs 1/173 (0.6%), p = 0.069).

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