Sex-stratified genome-wide association meta-analysis of major depressive disorder.

Nat Commun · 2025 · PMC12381276 · PMID 40858613

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hedged sentences

0.0000

closest p · 0.0× alpha

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boldest claim

The sentences

nominally significantP < 1 × 10 −6actually significant

No SNPs reached genome-wide significance, however four independent SNPs were nominally significant ( P < 1 × 10 −6 ) (Fig. 3 ).

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nearing significanceno p-value reported

Of the three female-specific regions (gwas-pw), two contain genome-wide significant SNPs in females only and the third includes a SNP nearing significance in females only (Supplementary Fig. 11 ).

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