DAOA and APOEε4 as Modifiers of Age of Onset in Autosomal-Dominant Early-Onset Alzheimer's Disease Caused by the PSEN1 A431E Variant.

Int J Mol Sci · 2025 · PMC12387094 · PMID 40869250

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did not reach statistical significanceno p-value reported

Interaction terms between APOE alleles and DAOA genotypes were included in the model but did not reach statistical significance.

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&lt;i&gt;DAOA&lt;/i&gt; and &lt;i&gt;APOEε4&lt;/i&gt; as Modifiers of Age of Onset in Autosomal-Dominant Early-Onset Alzheimer's Disease Caused by the &lt;i&gt;PSEN1&lt;/i&gt; A431E Variant.

The sentences

<i>DAOA</i> and <i>APOEε4</i> as Modifiers of Age of Onset in Autosomal-Dominant Early-Onset Alzheimer's Disease Caused by the <i>PSEN1</i> A431E Variant.