showed a trendp ‐value = 0.0884
Intriguingly, the treatment showed a trend to decrease cells viability when compared to vehicle ( p ‐value = 0.0884) and ZIF‐8 0.01 mg mL −1 ( p ‐value = 0.0710), whereas a significant decrease was observed when compared to lidocaine 0.01 mg mL −1 (Figure 6b ).