Weekly Cisplatin and 5-Fluorouracil in Neoadjuvant Chemoradiotherapy for Esophageal Cancer: A Pandemic-Era Evaluation.

Medicina (Kaunas) · 2025 · PMC12388350 · PMID 40870370

Europe PMC DOI

hedged sentences

0.0690

closest p · 1.4× alpha

0.0750

boldest claim

The sentences

did not reach statistical significancep = 0.069so close (0.05 < p ≤ 0.1)

four patients, 6.6%), although this difference did not reach statistical significance ( p = 0.069).

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a trend towards significancep = 0.075so close (0.05 < p ≤ 0.1)

In the multivariate analysis, PNI remained a significant independent predictor of worse PFS (HR: 2.83; 95% CI: 1.33–6.01; p = 0.007), while non-CR showed a trend towards significance (HR: 2.14; 95% CI: 0.93–4.95; p = 0.075).

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