Differential Impacts of Environmentally Relevant Microplastics on Gut Barrier Integrity in Mice Fed High-Fat Diet Versus Normal Chow Diet.

Metabolites · 2025 · PMC12388625 · PMID 40863173

Europe PMC DOI

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a decreasing trendno p-value reported

For IL-10, the HFD + water group showed a decreasing trend compared to the CD + water group, with no significant difference between the CD + water and CD + 8 mg/kg MP groups.

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did not reach statistical significanceno p-value reported

Our findings indicate that although the high-fat diet mice did not reach statistical significance, they still exhibited a discernible trend of change.

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an increasing trendno p-value reported

While IL-1β levels in the HFD + water group showed an increasing trend compared to the CD + water group, there was no significant statistical difference.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.