After analyzing by gender, this reduction was significantly observed in females, while in males there was a clear trend towards significance (Fig. 3 C).
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Tenofovir attenuates cytokine storm and bronchiolar damage in a mouse model of bleomycin-induced acute lung injury.
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Interestingly, preventive TDF treatment in BLM-challenged mice was associated with a decreasing trend in Ace and mRNA expression compared to the BLM group.