Evaluating tissue plasminogen activator (tPA) in dialysis catheter dysfunction: A focus on fibrin sheath and risk factors.

• Hypertension was associated with a 2.12-fold increase in the incidence rate of dysfunction (IRR = 2.12, 95 % CI: 0.94–4.79), though this did not reach statistical significance ( p = 0.070). • Diabetes mellitus (IRR = 0.78, 95 % CI: 0.25–2.37, p = 0.656) and smoking (IRR = 0.69, 95 % CI: 0.26–1.83, p = 0.457) were not significantly associated with dysfunction incidence.

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