Balancing efficacy and tolerability in metastatic pancreatic cancer: lessons from the ALPACA trial.

Hepatobiliary Surg Nutr · 2025 · PMC12393121 · PMID 40893742

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did not reach statistical significanceno p-value reported

Moreover, the alternating regimen showed benefits in patient-reported outcomes such as the Functional Assessment of Cancer Therapy-Taxane (FACT-Taxane) and European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30) scales, although the differences did not reach statistical significance in most cycles.

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