The transcriptional coordination of functional gene clusters is dependent on multiple chromatin remodelers in a haploid strain of the budding yeast, <i>Saccharomyces cerevisiae</i>.

The advent of greater resources and technologies in the intervening decades has revealed that position effects on gene expression can be quite significant, and highlights the importance of their impact as both a naturally regulatory mechanism as well as their implications for genetic modification and bioengineering applications ( Chen and Zhang, 2016 ; Wu et al., 2017 ; Arnone, 2020 ).

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