STAT3 haploinsufficiency is associated with autosomal dominant hyper-IgE syndrome.

Flow cytometry analysis showed a trend to a lower frequency of CD3 + γδ + T cells secreting IL-17A derived from Stat3 +/− infected mice in comparison with Stat3 WT cells; however, no statistical significances were observed, and a similar result was obtained for the IFN-γ–producing cells (fig.

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