Apigenin mitigates intestinal barrier dysfunction in sepsis by modulating the AKT signaling pathway.

BMC Gastroenterol · 2025 · PMC12398084 · PMID 40885907

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did not reach statistical significanceno p-value reported

Additionally, apigenin administration attenuated the levels of IL-1β ( P <0.05), TNF-α ( P <0.01) and IL-6 ( P <0.05), Although apigenin exhibited a downward trend in reducing COX-2 mRNA expression, the effect did not reach statistical significance.

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