Recombinant cathepsins B and L promote α-synuclein clearance and restore lysosomal function in human and murine models with α-synuclein pathology.

Mol Neurodegener · 2025 · PMC12398189 · PMID 40883786

Europe PMC DOI

hedged sentence

0.0569

closest p · 1.1× alpha

0.0569

boldest claim

The sentences

a strong trendp = 0.0569so close (0.05 < p ≤ 0.1)

Analyzing total human SNCA amounts by ELISA, a significant reduction was observed following rHsCTSB treatment, while rHsCTSL showed a strong trend towards reduction ( p = 0.0569; Figure S5 G).

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