A common variant of endothelial nitric oxide synthase (Glu298Asp) is associated with collateral development in patients with chronic coronary occlusions.

BMC Cardiovasc Disord · 2005 · PMC1239913 · PMID 16164743

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a strong trendno p-value reported

When considering the collateral flow grade, three variables were independently associated with an impaired collateral development: female gender, smoking, and the Asp 298 variant; there was also a strong trend for a deleterious effect of diabetes mellitus on collateral development.

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