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Assessing the Therapeutic Efficacy of Photodynamic Therapy, Fractional CO<sub>2</sub> Laser and Its Combination in the Treatment of Onychomycosis.

J Cosmet Dermatol · 2025 · PMC12399919 · PMID 40887881

Europe PMCDOI
1
hedged sentence
0.0760
closest p · 1.5× alpha
0.0760
boldest claim

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did not reach statistical significancep = 0.076so close (0.05 < p ≤ 0.1)
Severity index analysis indicated an improvement, with severe cases dropping from 73.3% to 26.7%, though this trend did not reach statistical significance ( p = 0.076). 3.2.2 Group B The Fractional CO 2 group follow‐up showed a significant reduction in KOH positivity, dropping from 100% pretreatment to 26.7% posttreatment ( p < 0.001), indicating effective fungal reduction.

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