a significant trendP < 0.001
Similarly, a population-based study from the USA found that the APR rate declined from 31.8% in 1998 to 19.2% in 2011, with a significant trend change in 2004 at 21.6% ( P < 0.001)[ 130 ].
Similarly, a population-based study from the USA found that the APR rate declined from 31.8% in 1998 to 19.2% in 2011, with a significant trend change in 2004 at 21.6% ( P < 0.001)[ 130 ].