Selective <i>endo</i>-Cyclic α-Functionalization of Saturated <i>N</i>-Alkyl Piperidines.

J Org Chem · 2025 · PMC12400421 · PMID 40820907

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closest p

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The sentences

a clear trendno p-value reported

Again, a clear trend was observed between endo -selectivity and the p K a H of the anion released, with acetyl chloride and bromide delivering the desired endo -iminium ion 3a in excellent assay yields.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

Selective &lt;i&gt;endo&lt;/i&gt;-Cyclic α-Functionalization of Saturated &lt;i&gt;N&lt;/i&gt;-Alkyl Piperidines.

The sentences

Selective <i>endo</i>-Cyclic α-Functionalization of Saturated <i>N</i>-Alkyl Piperidines.