Ontogenetic stage and type of donor cells shape extracellular vesicles' therapeutic potential for osteoarthritis.

The four different EV donor cell types yielded different numbers of particles/ml with fCCs and fMSCs producing approximately half as many particles/ml as P-MSCs and about 1/3 less than WJ-MSC-EVs (Table 1 ), however the differences did not reach statistical significance ( p = 0.6799).

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