Microbiome meets immunotherapy: unlocking the hidden predictors of immune checkpoint inhibitors.

NPJ Biofilms Microbiomes · 2025 · PMC12405452 · PMID 40897718

Europe PMC DOI

hedged sentences

0.0480

closest p · 1.0× alpha

0.3400

boldest claim

The sentences

marginally significantP = 0.048actually significant

When stratified by tumor type, the analysis of three cohorts focusing on hepatobiliary cancers showed a marginally significant association between viral status and SAEs (RR = 0.62, 95% CI: 0.39–1.00, P = 0.048, N = 3).

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did not reach statistical significanceP = 0.34not close (p > 0.1)

S1A ), but this funnel plot asymmetry did not reach statistical significance (Egger’s test: t = −0.97, P = 0.34).

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